بررسی تاثیر مقدار کم کتامین بر گلو درد بعد از عمل تانسیلکتومی در کودکان

Background and aims: Ketamine efficacy as an analgesic adjuvant has been studied inseveral clinical settings with conflicting results. Sore throat and pain after swallowingfollowing tonsillectomy is significant. The aim of this study was to investigate the effect of lowdose ketamine on sore throat (pain) after tonsillectomy.Materials and methods: In this double blind clinical trial, fifty children were, divided intotwo equal groups of Ketamine and control. The subjects aged 4-14 years old and physical ASAclass I-II were randomized to receive pemedication with either ketamine 0.lmg/kg I.V. orplacebo, 5 minutes before induction of a standard general anesthesia.Results: The ketamine group showed significantly lower pain scores with less totalpethidine consumption (P<0.005) during 6h after surgery. The mean pain score in ketaminegroup was 1.32±1.02 and in control group was 2.4±1.25. There were no differences in theincidence of vomiting between the groups.Conclusion: Premedication with a small dose of ketamine reduces pain after tonsillectomyin children who received an analgesic regimen combined with an opioid.